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Ring-shaped Rad51 Paralog Protein Complexes Bind Holliday Junctions and Replication Forks as Visualized by Electron Microscopy

In mammals, there are five Rad51 paralogs that form two distinct complexes in vivo. One complex is composed of Rad51B-Rad51C-Rad51D-Xrcc2 (BCDX2) and the other Rad51C-Xrcc3 (CX3). We co-expressed and purified human BCDX2 and CX3 protein complexes from insect cells and investigated their binding pref...

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Detalhes bibliográficos
Main Authors: Compton, Sarah A., Özgür, Sezgin, Griffith, Jack D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859493/
https://ncbi.nlm.nih.gov/pubmed/20207730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.074286
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