A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

Mutations in the inositol 5-phosphatase OCRL are responsible for Lowe syndrome, whose manifestations include mental retardation and renal Fanconi syndrome. OCRL has been implicated in membrane traffic, but disease mechanisms remain unclear. We show that OCRL visits late stage endocytic clathrin coat...

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Autori principali: Erdmann, Kai S., Mao, Yuxin, McCrea, Heather J., Zoncu, Roberto, Lee, Sangyoon, Paradise, Summer, Modregger, Jan, Biemesderfer, Daniel, Toomre, Derek, De Camilli, Pietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025683/
https://ncbi.nlm.nih.gov/pubmed/17765681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.08.004
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