A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway

Mutations in the inositol 5-phosphatase OCRL are responsible for Lowe syndrome, whose manifestations include mental retardation and renal Fanconi syndrome. OCRL has been implicated in membrane traffic, but disease mechanisms remain unclear. We show that OCRL visits late stage endocytic clathrin coat...

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Hlavní autoři: Erdmann, Kai S., Mao, Yuxin, McCrea, Heather J., Zoncu, Roberto, Lee, Sangyoon, Paradise, Summer, Modregger, Jan, Biemesderfer, Daniel, Toomre, Derek, De Camilli, Pietro
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025683/
https://ncbi.nlm.nih.gov/pubmed/17765681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.08.004
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