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Enzyme Localization Can Drastically Affect Signal Amplification in Signal Transduction Pathways

Push–pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity. In a push–pull network, two antagonistic enzymes control the activity of a protein by covalent mo...

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Bibliografiset tiedot
Päätekijät: van Albada, Siebe B, ten Wolde, Pieter Rein
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014792/
https://ncbi.nlm.nih.gov/pubmed/17937496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030195
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