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Enzyme Localization Can Drastically Affect Signal Amplification in Signal Transduction Pathways
Push–pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity. In a push–pull network, two antagonistic enzymes control the activity of a protein by covalent mo...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014792/ https://ncbi.nlm.nih.gov/pubmed/17937496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030195 |
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