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Enzyme Localization Can Drastically Affect Signal Amplification in Signal Transduction Pathways

Push–pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity. In a push–pull network, two antagonistic enzymes control the activity of a protein by covalent mo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: van Albada, Siebe B, ten Wolde, Pieter Rein
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014792/
https://ncbi.nlm.nih.gov/pubmed/17937496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030195
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