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Diffusion of Transcription Factors Can Drastically Enhance the Noise in Gene Expression

We study by Green's Function Reaction Dynamics the effect of the diffusive motion of repressor molecules on the noise in mRNA and protein levels for a gene that is under the control of a repressor. We find that spatial fluctuations due to diffusion can drastically enhance the noise in gene expr...

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Detalhes bibliográficos
Main Authors: van Zon, Jeroen S., Morelli, Marco J., Tănase-Nicola, Sorin, ten Wolde, Pieter Rein
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779939/
https://ncbi.nlm.nih.gov/pubmed/17012327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.086157
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