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Reaction Coordinates for the Flipping of Genetic Switches
We present a detailed analysis, based on the forward flux sampling simulation method, of the switching dynamics and stability of two models of genetic toggle switches, consisting of two mutually repressing genes encoding transcription factors (TFs); in one model (the exclusive switch), the two trans...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292366/ https://ncbi.nlm.nih.gov/pubmed/18222998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.116699 |
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