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Reaction Coordinates for the Flipping of Genetic Switches
We present a detailed analysis, based on the forward flux sampling simulation method, of the switching dynamics and stability of two models of genetic toggle switches, consisting of two mutually repressing genes encoding transcription factors (TFs); in one model (the exclusive switch), the two trans...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
The Biophysical Society
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2292366/ https://ncbi.nlm.nih.gov/pubmed/18222998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.116699 |
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