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Spatio-temporal correlations can drastically change the response of a MAPK pathway
Multisite covalent modification of proteins is omnipresent in eukaryotic cells. A well-known example is the mitogen-activated protein kinase (MAPK) cascade where, in each layer of the cascade, a protein is phosphorylated at two sites. It has long been known that the response of a MAPK pathway strong...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811204/ https://ncbi.nlm.nih.gov/pubmed/20133748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906885107 |
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