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The Robustness of Proofreading to Crowding-Induced Pseudo-Processivity in the MAPK Pathway
Double phosphorylation of protein kinases is a common feature of signaling cascades. This motif may reduce cross-talk between signaling pathways because the second phosphorylation site allows for proofreading, especially when phosphorylation is distributive rather than processive. Recent studies sug...
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| Publicado en: | Biophys J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241453/ https://ncbi.nlm.nih.gov/pubmed/25418311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.020 |
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