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The Robustness of Proofreading to Crowding-Induced Pseudo-Processivity in the MAPK Pathway

Double phosphorylation of protein kinases is a common feature of signaling cascades. This motif may reduce cross-talk between signaling pathways because the second phosphorylation site allows for proofreading, especially when phosphorylation is distributive rather than processive. Recent studies sug...

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Bibliografski detalji
Izdano u:Biophys J
Glavni autori: Ouldridge, Thomas E., Rein ten Wolde, Pieter
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4241453/
https://ncbi.nlm.nih.gov/pubmed/25418311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.10.020
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