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Diffusion of Transcription Factors Can Drastically Enhance the Noise in Gene Expression

We study by Green's Function Reaction Dynamics the effect of the diffusive motion of repressor molecules on the noise in mRNA and protein levels for a gene that is under the control of a repressor. We find that spatial fluctuations due to diffusion can drastically enhance the noise in gene expr...

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Bibliografiske detaljer
Main Authors: van Zon, Jeroen S., Morelli, Marco J., Tănase-Nicola, Sorin, ten Wolde, Pieter Rein
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779939/
https://ncbi.nlm.nih.gov/pubmed/17012327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.086157
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