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Interim analyses and sequential designs in phase III studies
Recruitment of patients to a clinical trial usually occurs over a period of time, resulting in the steady accumulation of data throughout the trial's duration. Yet, according to traditional statistical methods, the sample size of the trial should be determined in advance, and data collected on...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014474/ https://ncbi.nlm.nih.gov/pubmed/11421995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01382.x |
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