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Comparison of Bayesian and frequentist group-sequential clinical trial designs

BACKGROUND: There is a growing interest in the use of Bayesian adaptive designs in late-phase clinical trials. This includes the use of stopping rules based on Bayesian analyses in which the frequentist type I error rate is controlled as in frequentist group-sequential designs. METHODS: This paper p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Med Res Methodol
Prif Awduron: Stallard, Nigel, Todd, Susan, Ryan, Elizabeth G., Gates, Simon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947872/
https://ncbi.nlm.nih.gov/pubmed/31910813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-019-0892-8
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