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Comparison of Bayesian and frequentist group-sequential clinical trial designs

BACKGROUND: There is a growing interest in the use of Bayesian adaptive designs in late-phase clinical trials. This includes the use of stopping rules based on Bayesian analyses in which the frequentist type I error rate is controlled as in frequentist group-sequential designs. METHODS: This paper p...

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Detalhes bibliográficos
Publicado no:BMC Med Res Methodol
Main Authors: Stallard, Nigel, Todd, Susan, Ryan, Elizabeth G., Gates, Simon
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6947872/
https://ncbi.nlm.nih.gov/pubmed/31910813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-019-0892-8
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