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Do we need to adjust for interim analyses in a Bayesian adaptive trial design?
BACKGROUND: Bayesian adaptive methods are increasingly being used to design clinical trials and offer several advantages over traditional approaches. Decisions at analysis points are usually based on the posterior distribution of the treatment effect. However, there is some confusion as to whether c...
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| Published in: | BMC Med Res Methodol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7288484/ https://ncbi.nlm.nih.gov/pubmed/32522284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01042-7 |
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