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Do we need to adjust for interim analyses in a Bayesian adaptive trial design?
BACKGROUND: Bayesian adaptive methods are increasingly being used to design clinical trials and offer several advantages over traditional approaches. Decisions at analysis points are usually based on the posterior distribution of the treatment effect. However, there is some confusion as to whether c...
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| 出版年: | BMC Med Res Methodol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7288484/ https://ncbi.nlm.nih.gov/pubmed/32522284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01042-7 |
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