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Do we need to adjust for interim analyses in a Bayesian adaptive trial design?

BACKGROUND: Bayesian adaptive methods are increasingly being used to design clinical trials and offer several advantages over traditional approaches. Decisions at analysis points are usually based on the posterior distribution of the treatment effect. However, there is some confusion as to whether c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Med Res Methodol
Egile Nagusiak: Ryan, Elizabeth G., Brock, Kristian, Gates, Simon, Slade, Daniel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288484/
https://ncbi.nlm.nih.gov/pubmed/32522284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01042-7
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