Llwytho...

Learning from previous responses in phase I dose-escalation studies

Dose escalation in phase I studies is generally performed on the basis of clinical experience and judgement. In this paper some of the statistical approaches that have been proposed for the formalization of the procedure are described. Apart from the use of the Continual Reassessment Method in oncol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Whitehead, John, Zhou, Yinghui, Stallard, Nigel, Todd, Susan, Whitehead, Anne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014510/
https://ncbi.nlm.nih.gov/pubmed/11453884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01383.x
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