Nalaganje...
Learning from previous responses in phase I dose-escalation studies
Dose escalation in phase I studies is generally performed on the basis of clinical experience and judgement. In this paper some of the statistical approaches that have been proposed for the formalization of the procedure are described. Apart from the use of the Continual Reassessment Method in oncol...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014510/ https://ncbi.nlm.nih.gov/pubmed/11453884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01383.x |
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