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Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics

AIMS: Fosinoprilat, the active product of fosinopril, is eliminated by an hepatic pathway in addition to the renal pathway shared by other angiotensin converting enzyme inhibitors (ACEIs). This study aimed to determine whether impaired renal function affects the pharmacokinetics and pharmacodynamics...

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Autori principali: O’Grady, Padraig, Yee, Kan-Fat, Lins, Robert, Mangold, Bernhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014346/
https://ncbi.nlm.nih.gov/pubmed/10510149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00013.x
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