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Single dose and steady state pharmacokinetics and pharmacodynamics of the ACE-inhibitor imidapril in hypertensive patients
AIMS: To investigate the pharmacokinetic profile of the ACE-inhibitor imidapril in 10 hypertensive patients after a first single dose (10 mg) and after 28 days therapy with imidapril 10 mg once daily. METHODS: C(max), t(max), t(1/2) and AUC of imidapril and imidaprilat were obtained. ACE-activity an...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1873968/ https://ncbi.nlm.nih.gov/pubmed/9578185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.t01-1-00694.x |
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