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Pharmacokinetic and pharmacodynamic interaction trial after repeated oral doses of imdapril and digoxin in healthy volunteers

Aims To investigate the potential pharmacokinetic and pharmacodynamic interaction between imidapril and digoxin. Methods AUC, C(max )and t(max) of imidapril, imidaprilat and digoxin were calculated and evaluated in a randomized, doubleblind three-period cross-over design in 12 healthy volunteers aft...

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Bibliografiske detaljer
Main Authors: Harder, Sebastian, Thürmann, Petra A.
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042776/
https://ncbi.nlm.nih.gov/pubmed/9159562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1997.00588.x
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