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Effect of multiple doses of losartan on the pharmacokinetics of single doses of digoxin in healthy volunteers.

1. Losartan (DuP 753, MK-954) is a novel, potent and highly selective AT1 angiotensin II receptor antagonist. The effect of multiple oral doses of losartan on digoxin pharmacokinetics was evaluated in healthy male subjects. 2. In a double-blind and randomized fashion, subjects received 50 mg losarta...

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Detalhes bibliográficos
Main Authors: De Smet, M, Schoors, D F, De Meyer, G, Verbesselt, R, Goldberg, M R, Fitzpatrick, V, Somers, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1365213/
https://ncbi.nlm.nih.gov/pubmed/8703664
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