Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics

AIMS: Fosinoprilat, the active product of fosinopril, is eliminated by an hepatic pathway in addition to the renal pathway shared by other angiotensin converting enzyme inhibitors (ACEIs). This study aimed to determine whether impaired renal function affects the pharmacokinetics and pharmacodynamics...

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Autores principales: O’Grady, Padraig, Yee, Kan-Fat, Lins, Robert, Mangold, Bernhard
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 1999
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014346/
https://ncbi.nlm.nih.gov/pubmed/10510149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00013.x
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