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Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics

AIMS: Fosinoprilat, the active product of fosinopril, is eliminated by an hepatic pathway in addition to the renal pathway shared by other angiotensin converting enzyme inhibitors (ACEIs). This study aimed to determine whether impaired renal function affects the pharmacokinetics and pharmacodynamics...

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Bibliografiske detaljer
Main Authors: O’Grady, Padraig, Yee, Kan-Fat, Lins, Robert, Mangold, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014346/
https://ncbi.nlm.nih.gov/pubmed/10510149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00013.x
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