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Pharmacokinetics and pharmacodynamics of warfarin at steady state.

1 The relationship between warfarin dose, total and free plasma warfarin concentration, and anticoagulant effect was examined at several steady-state levels in fifteen patients during withdrawal of warfarin therapy. 2 Total plasma clearance was significantly correlated with the free fraction in plas...

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Detalhes bibliográficos
Main Authors: Routledge, P A, Chapman, P H, Davies, D M, Rawlins, M D
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1429794/
https://ncbi.nlm.nih.gov/pubmed/497091
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