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Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics

AIMS: Fosinoprilat, the active product of fosinopril, is eliminated by an hepatic pathway in addition to the renal pathway shared by other angiotensin converting enzyme inhibitors (ACEIs). This study aimed to determine whether impaired renal function affects the pharmacokinetics and pharmacodynamics...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: O’Grady, Padraig, Yee, Kan-Fat, Lins, Robert, Mangold, Bernhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014346/
https://ncbi.nlm.nih.gov/pubmed/10510149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00013.x
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