A PMLRARα transgene initiates murine acute promyelocytic leukemia

The malignant cells of acute promyelocytic leukemia (APL) contain a reciprocal chromosomal translocation that fuses the promyelocytic leukemia gene (PML) with the retinoic acid receptor α gene (RARα). To test the hypothesis that the chimera PMLRARα plays a role in leukemogenesis, we expressed a PMLR...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Brown, Diane, Kogan, Scott, Lagasse, Eric, Weissman, Irving, Alcalay, Myriam, Pelicci, Pier Giuseppe, Atwater, Susan, Bishop, J. Michael
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20126/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122233/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2551
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