A PMLRARα transgene initiates murine acute promyelocytic leukemia

The malignant cells of acute promyelocytic leukemia (APL) contain a reciprocal chromosomal translocation that fuses the promyelocytic leukemia gene (PML) with the retinoic acid receptor α gene (RARα). To test the hypothesis that the chimera PMLRARα plays a role in leukemogenesis, we expressed a PMLR...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Brown, Diane, Kogan, Scott, Lagasse, Eric, Weissman, Irving, Alcalay, Myriam, Pelicci, Pier Giuseppe, Atwater, Susan, Bishop, J. Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC20126/
https://ncbi.nlm.nih.gov/pubmed/9122233
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky