COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

Efficient formation of scrapie isoform of prion protein (PrP(Sc)) requires targeting PrP(Sc) by glycophosphatidyl inositol (GPI) anchors to caveolae-like domains (CLDs). Redirecting the cellular isoform of prion protein (PrP(C)) to clathrin-coated pits by creating chimeric PrP molecules with four di...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Kaneko, Kiyotoshi, Vey, Martin, Scott, Michael, Pilkuhn, Susanne, Cohen, Fred E., Prusiner, Stanley B.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20088/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122195/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2333
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