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Primary structure of prion protein may modify scrapie isolate properties.

Scrapie is an infectious neurodegenerative disease caused by unusual pathogens called prions, in which no scrapie-specific nucleic acid has been detected to date. The only known component of the prion is the scrapie isoform of prion protein (PrPSc), which is encoded by a host gene (Prn-p). Isolates...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Carlson, G A, Westaway, D, DeArmond, S J, Peterson-Torchia, M, Prusiner, S B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298087/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2798418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.19.7475
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