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Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice

There is considerable concern that bovine prions from cattle with bovine spongiform encephalopathy (BSE) may have been passed to humans (Hu), resulting in a new form of Creutzfeldt–Jakob disease (CJD). We report here the transmission of bovine (Bo) prions to transgenic (Tg) mice expressing BoPrP; on...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Scott, Michael R., Safar, Jiri, Telling, Glenn, Nguyen, Oanh, Groth, Darlene, Torchia, Marilyn, Koehler, Ruth, Tremblay, Patrick, Walther, Dirk, Cohen, Fred E., DeArmond, Stephen J., Prusiner, Stanley B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
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Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14279
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