Identification of a prion protein epitope modulating transmission of bovine spongiform encephalopathy prions to transgenic mice

There is considerable concern that bovine prions from cattle with bovine spongiform encephalopathy (BSE) may have been passed to humans (Hu), resulting in a new form of Creutzfeldt–Jakob disease (CJD). We report here the transmission of bovine (Bo) prions to transgenic (Tg) mice expressing BoPrP; on...

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Autors principals: Scott, Michael R., Safar, Jiri, Telling, Glenn, Nguyen, Oanh, Groth, Darlene, Torchia, Marilyn, Koehler, Ruth, Tremblay, Patrick, Walther, Dirk, Cohen, Fred E., DeArmond, Stephen J., Prusiner, Stanley B.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24939/
https://ncbi.nlm.nih.gov/pubmed/9405603
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