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Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

There is growing concern that bovine spongiform encephalopathy (BSE) may have passed from cattle to humans. We report here that transgenic (Tg) mice expressing bovine (Bo) prion protein (PrP) serially propagate BSE prions and that there is no species barrier for transmission from cattle to Tg(BoPrP)...

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Detalhes bibliográficos
Main Authors: Scott, Michael R., Will, Robert, Ironside, James, Nguyen, Hoang-Oanh B., Tremblay, Patrick, DeArmond, Stephen J., Prusiner, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24786/
https://ncbi.nlm.nih.gov/pubmed/10611351
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