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Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans

There is growing concern that bovine spongiform encephalopathy (BSE) may have passed from cattle to humans. We report here that transgenic (Tg) mice expressing bovine (Bo) prion protein (PrP) serially propagate BSE prions and that there is no species barrier for transmission from cattle to Tg(BoPrP)...

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Bibliografiske detaljer
Main Authors: Scott, Michael R., Will, Robert, Ironside, James, Nguyen, Hoang-Oanh B., Tremblay, Patrick, DeArmond, Stephen J., Prusiner, Stanley B.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24786/
https://ncbi.nlm.nih.gov/pubmed/10611351
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