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Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.

Different prion isolates, often referred to as "strains," present an enigma because considerable evidence argues that prions are devoid of nucleic acid. To investigate prion diversity, we inoculated three "strains" of prions into congenic and transgenic mice harboring variable numbers of two differe...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Carlson, G A, Ebeling, C, Yang, S L, Telling, G, Torchia, M, Groth, D, Westaway, D, DeArmond, S J, Prusiner, S B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7911243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5690
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