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Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism
BACKGROUND: Microvascular injury plays a key role in normal tissue radiation responses. Statins, in addition to their lipid-lowering effects, have vasculoprotective properties that may counteract some effects of radiation on normal tissues. We examined whether administration of simvastatin ameliorat...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2000701/ https://ncbi.nlm.nih.gov/pubmed/17674978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2007.03.036 |
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