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Activation of Protease Activated Receptor 2 (PAR(2)) by an Exogenous Agonist Exacerbates Early Radiation Injury in Rat Intestine
PURPOSE: Protease-activated receptor-2 (PAR(2)) is highly expressed throughout the gut and regulates inflammatory, mitogenic, fibroproliferative, and nociceptive responses to injury. PAR(2) is strikingly upregulated and exhibits increased activation in response to intestinal irradiation. We examined...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901891/ https://ncbi.nlm.nih.gov/pubmed/20610041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.12.075 |
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