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Activation of Protease Activated Receptor 2 (PAR(2)) by an Exogenous Agonist Exacerbates Early Radiation Injury in Rat Intestine

PURPOSE: Protease-activated receptor-2 (PAR(2)) is highly expressed throughout the gut and regulates inflammatory, mitogenic, fibroproliferative, and nociceptive responses to injury. PAR(2) is strikingly upregulated and exhibits increased activation in response to intestinal irradiation. We examined...

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Bibliografski detalji
Glavni autori: Wang, Junru, Boerma, Marjan, Kulkarni, Ashwini, Hollenberg, Morley D., Hauer-Jensen, Martin
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901891/
https://ncbi.nlm.nih.gov/pubmed/20610041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.12.075
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