Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice

Following myocardial infarction, nonischemic myocyte death results in infarct expansion, myocardial loss, and ventricular dysfunction. Here, we demonstrate that a specific proapoptotic gene, Bnip3, minimizes ventricular remodeling in the mouse, despite having no effect on early or late infarct size....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Diwan, Abhinav, Krenz, Maike, Syed, Faisal M., Wansapura, Janaka, Ren, Xiaoping, Koesters, Andrew G., Li, Hairong, Kirshenbaum, Lorrie A., Hahn, Harvey S., Robbins, Jeffrey, Jones, W. Keith, Dorn, Gerald W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994631/
https://ncbi.nlm.nih.gov/pubmed/17909626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32490
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados