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Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death
Hypoxia-inducible pro-death protein BNIP3 (BCL-2/adenovirus E1B 19-kDa interacting protein 3), provokes mitochondrial permeabilization causing cardiomyocyte death in ischemia-reperfusion injury. Inhibition of autophagy accelerates BNIP3-induced cell death, by preventing removal of damaged mitochondr...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3337840/ https://ncbi.nlm.nih.gov/pubmed/22302006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.18658 |
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