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Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death

Hypoxia-inducible pro-death protein BNIP3 (BCL-2/adenovirus E1B 19-kDa interacting protein 3), provokes mitochondrial permeabilization causing cardiomyocyte death in ischemia-reperfusion injury. Inhibition of autophagy accelerates BNIP3-induced cell death, by preventing removal of damaged mitochondr...

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Detalhes bibliográficos
Main Authors: Ma, Xiucui, Godar, Rebecca J., Liu, Haiyan, Diwan, Abhinav
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337840/
https://ncbi.nlm.nih.gov/pubmed/22302006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.18658
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