Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway

Obesity-induced diabetes is characterized by hyperglycemia, insulin resistance, and progressive beta cell failure. In islets of mice with obesity-induced diabetes, we observe increased beta cell death and impaired autophagic flux. We hypothesized that intermittent fasting, a clinically sustainable t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Autophagy
Egile Nagusiak: Liu, Haiyan, Javaheri, Ali, Godar, Rebecca J., Murphy, John, Ma, Xiucui, Rohatgi, Nidhi, Mahadevan, Jana, Hyrc, Krzysztof, Saftig, Paul, Marshall, Connie, McDaniel, Michael L., Remedi, Maria S., Razani, Babak, Urano, Fumihiko, Diwan, Abhinav
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2017
Gaiak:
Research Paper - Basic Science
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788488/
https://ncbi.nlm.nih.gov/pubmed/28853981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1368596
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