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TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA
Erk1/Erk2 MAP kinases are key regulators of cell behaviour and their activation is generally associated with tyrosine kinase signalling. However, TGF-β stimulation also activates Erk MAP kinases through an undefined mechanism, albeit to a much lower level than receptor tyrosine kinase stimulation. W...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1994119/ https://ncbi.nlm.nih.gov/pubmed/17673906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601818 |
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