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ShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigen

ShcA and Grb2 are crucial components in signalling by most tyrosine kinase-associated receptors. How ever, it is not clear whether Grb2 bound directly to the receptor is equivalent to Grb2 associated via ShcA. We have used signalling stimulated by the middle T-antigen (MT) of polyoma virus to addres...

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Detalhes bibliográficos
Main Authors: Nicholson, Philippa R., Empereur, Sylvie, Glover, Hilary R., Dilworth, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC125738/
https://ncbi.nlm.nih.gov/pubmed/11707405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.22.6337
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