ShcA tyrosine phosphorylation sites can replace ShcA binding in signalling by middle T-antigen

ShcA and Grb2 are crucial components in signalling by most tyrosine kinase-associated receptors. How ever, it is not clear whether Grb2 bound directly to the receptor is equivalent to Grb2 associated via ShcA. We have used signalling stimulated by the middle T-antigen (MT) of polyoma virus to addres...

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Publié dans:	EMBO J
Auteurs principaux:	Nicholson, Philippa R., Empereur, Sylvie, Glover, Hilary R., Dilworth, Stephen M.
Format:	Artigo
Langue:	Inglês
Publié:	Nature Publishing Group 2001
Sujets:	Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.22.6337
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