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Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes

In early diabetes, the kidney grows and the glomerular filtration rate (GFR) increases. This growth is linked to ornithine decarboxylase (ODC). The study of hyperfiltration has focused on microvascular abnormalities, but hyperfiltration may actually result from a prior increase in capacity for proxi...

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Autors principals: Thomson, Scott C., Deng, Aihua, Bao, Dingjiu, Satriano, Joseph, Blantz, Roland C., Vallon, Volker
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC199175/
https://ncbi.nlm.nih.gov/pubmed/11160138
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