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Adenosine formed by 5′-nucleotidase mediates tubuloglomerular feedback

Nephron function is stabilized by tubuloglomerular feedback (TGF). TGF operates within the juxtaglomerular apparatus, sensing changes in tubular flow and eliciting compensatory changes in single nephron GFR (SNGFR). The mediator(s) of TGF remains unconfirmed. One theory is that ATP consumed in activ...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Thomson, Scott, Bao, Dingjiu, Deng, Aihua, Vallon, Volker
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2000
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10903345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8761
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