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Adenosine formed by 5′-nucleotidase mediates tubuloglomerular feedback

Nephron function is stabilized by tubuloglomerular feedback (TGF). TGF operates within the juxtaglomerular apparatus, sensing changes in tubular flow and eliciting compensatory changes in single nephron GFR (SNGFR). The mediator(s) of TGF remains unconfirmed. One theory is that ATP consumed in activ...

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Pubblicato in:J Clin Invest
Autori principali: Thomson, Scott, Bao, Dingjiu, Deng, Aihua, Vallon, Volker
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10903345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8761
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