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The tubular hypothesis of nephron filtration and diabetic kidney disease

Kidney size and glomerular filtration rate (GFR) often increase with the onset of diabetes, and elevated GFR is a risk factor for the development of diabetic kidney disease. Hyperfiltration mainly occurs in response to signals passed from the tubule to the glomerulus: high levels of glucose in the g...

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Detalhes bibliográficos
Publicado no:Nat Rev Nephrol
Main Authors: Vallon, Volker, Thomson, Scott C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242158/
https://ncbi.nlm.nih.gov/pubmed/32152499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41581-020-0256-y
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