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Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes

In early diabetes, the kidney grows and the glomerular filtration rate (GFR) increases. This growth is linked to ornithine decarboxylase (ODC). The study of hyperfiltration has focused on microvascular abnormalities, but hyperfiltration may actually result from a prior increase in capacity for proxi...

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Detalhes bibliográficos
Main Authors: Thomson, Scott C., Deng, Aihua, Bao, Dingjiu, Satriano, Joseph, Blantz, Roland C., Vallon, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC199175/
https://ncbi.nlm.nih.gov/pubmed/11160138
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