Adenosine A(1) Receptors Determine Glomerular Hyperfiltration and the Salt Paradox in Early Streptozotocin Diabetes Mellitus

BACKGROUND: In early type 1 diabetes mellitus, changes in proximal reabsorption influence glomerular filtration rate (GFR) through tubuloglomerular feedback (TGF). Due to TGF, a primary increase in proximal reabsorption causes early diabetic hyperfiltration, while a heightened sensitivity of the pro...

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Main Authors: Vallon, Volker, Schroth, Jana, Satriano, Joseph, Blantz, Roland C., Thomson, Scott C., Rieg, Timo
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2009
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904473/
https://ncbi.nlm.nih.gov/pubmed/19276628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000208211
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