Rational design of a triple helix-specific intercalating ligand

DNA triple helices offer new perspectives toward oligonucleotide-directed gene regulation. However, the poor stability of some of these structures might limit their use under physiological conditions. Specific ligands can intercalate into DNA triple helices and stabilize them. Molecular modeling and...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Escudé, Christophe, Nguyen, Chi Hung, Kukreti, Shrikant, Janin, Yves, Sun, Jian-Sheng, Bisagni, Emile, Garestier, Thérèse, Hélène, Claude
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1998
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19880/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3591
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!